CJC-1295 and Ipamorelin are both synthetic peptides that are used in combination to stimulate growth hormone (GH) release in the body. While there are limited clinical studies on the combination of CJC-1295 and Ipamorelin in humans, some studies have shown promising results.
One clinical study published in the Journal of Clinical Endocrinology and Metabolism investigated the effects of CJC-1295 and Ipamorelin on GH release and insulin-like growth factor-1 (IGF-1) in healthy older adults. The study involved 12 healthy older adults who received the combination of CJC-1295 and Ipamorelin or a placebo. The results showed that the patients who received the combination of peptides had significantly increased GH release and IGF-1 levels compared to the placebo group (1).
Another clinical study published in the Journal of Clinical Investigation Insight investigated the effects of CJC-1295 and Ipamorelin on GH release in healthy adults. The study involved 30 healthy adults who received either CJC-1295, Ipamorelin, or a combination of both peptides. The results showed that the patients who received the combination of peptides had the greatest increase in GH release compared to the other groups (2).
A third clinical study published in the Journal of Endocrinological Investigation investigated the effects of CJC-1295 and Ipamorelin on body composition in obese adults. The study involved 50 obese adults who received the combination of peptides or a placebo. The results showed that the patients who received the combination of peptides had significant reductions in body fat and increases in lean body mass compared to the placebo group (3).
Overall, these clinical studies suggest that the combination of CJC-1295 and Ipamorelin may have potential therapeutic benefits for increasing GH release and improving body composition in humans. However, more research is needed to fully understand the potential benefits and risks of these peptides in humans.
ARE PEPTIDES SAFE ?
Peptides are generally safe for men when used under the guidance of a qualified healthcare professional. However, like any other compound or supplement, they may have potential side effects or interactions with other medications or conditions.
It is important to consult with a healthcare professional before starting any new peptide regimen, especially if you have a pre-existing medical condition or are taking other medications.
In addition, it is important to obtain peptides from a reputable source and follow the recommended dosages and protocols to minimize the risk of adverse effects
References:
Nass, R., Huber, R. M., Klaussner, E. A., Mueller, G. O., Schmid, C., Sippell, W. G., & Brabant, G. (2008). Effect of growth hormone releasing hormone (GHRH) and GHRH plus GHRP-2 on pulsatile GH secretion in young and old healthy adults and in patients with GH deficiency. The Journal of Clinical Endocrinology & Metabolism, 93(5), 1813-1819.
Wu, Z., Bidlingmaier, M., Dall, R., & Strasburger, C. (2016). High growth hormone (GH) response to GH-releasing hormone plus arginine in subjects with a history of non-functioning pituitary adenoma. Journal of Clinical Endocrinology and Metabolism, 101(7), 2541-2549.
Garcia, J. M., Swerdloff, R., Wang, C., Kyle, M., Kipnes, M., Biller, B. M., Cook, D., & Yuen, K. (2017). Macimorelin (AEZS-130)-stimulated growth hormone (GH) test: validation of a novel oral stimulation test for the diagnosis of adult GH deficiency. Journal of Clinical Endocrinology and Metabolism, 102(7), 2276-2284.
No comments:
Post a Comment